|
12 May |
| 16:00 |
Registration Opens |
|
| 18:00 - 20:00 |
Welcome Reception at the Historic Carolina Inn |
|
| 13 May
|
Session I:
Systems Biology |
Chairs: Konrad Reinhart/John
Marshall |
| 09:00 - 09:25 |
Systems Biology - Practice and Challenges |
Michael Yaffe, USA |
| 09:25 - 09:50 |
Lessons Learned from the Co-evolution Between the Mammal Innate
Immune System and the Microbial Community |
Phillippe Sansonetti, France |
| 09:50 - 10:15 |
How Holistic "Microbial Community" Approaches will lead to
better Anti-infective Strategies |
Margaret Riley, USA |
| 10:15 - 10:45 |
Coffee Break |
|
| 10:45 - 11:10 |
Systems Biology of Infection: Potential and
Challenges |
Dick Bumann, CH |
| 11:10 - 11:35 |
How Far can a Systems Biology Approach Help to Predict the
Outcome in Clinical Research? |
Steven Chang, USA |
| 11:35 - 12:30 |
Lunch |
|
| |
Session II: Genomics |
Chairs: Jean-Francois Dhainaut/Steven Opal |
| 12:30- 13:15 |
Genetic Background, Morbidity and Development of Multi-organ
Failure-What has been Proven? |
Derek Angus,USA |
| 13:15 - 13:40 |
Genetic Predisposition to Infection and Sepsis - Fact or
Fiction? |
Jean-Paul Mira, France |
| 13:40 - 14:05 |
Parmacogenomics - Lessons Learnt from Other Fields |
D B Goldstein, USA |
| 14:05 - 14:30 |
Break |
|
| |
Session III: The Challenges in
Sepsis Research |
Chairs; Thierry Calandra/Dereck Angus |
| 14:30 - 14:55 |
Sepsis as a Complex Non-Linear Syndrome - and the Limitations of
Single Molecule Approaches |
Tim Buchman, USA |
| 14:55 - 15:20 |
The Limitations of Current Sepsis Diagnosis and Inclusion
Critirea in Clinical Sepsis Trials |
John Marshall, CDA |
| 15:20 - 15:45 |
Functional Neuroanatomy of the Cytokine Network: Implications
for Target Identification and Drug Discovery |
Kevin Tracey, USA |
| 15:45 - 16:15 |
Panel Discussion |
|
| 19:00 |
Dinner at the
Historic Carolina Inn |
|
| 14 May |
Session IV:
The Challenges in Pathogen Detection and Diagnosis of Infection |
Chairs: Jean-francois Dhainaut/Tom
Van der Poll |
| 08:30 - 08:55 |
Pathogen Functional Genomics in Yeast Infection |
Bernhard Hube, GE |
| 08:55 - 09:20 |
The Role of Detection and Rapid Diagnosis in Treating Infection
and Sepsis |
Thierry Calandra, CH |
| 09:20 - 09:45 |
The Potential and Limitations of Current Sepsis
Markers |
Konrad Reinhart, GE |
| 09:45 - 10:10 |
The Clinical Impact of Pathogen Resistance |
Steven Opal, USA |
| 10:10 - 10:35 |
The Question of Resistance: Why does it develop and
future ways to detect it? |
Gerry Wright, CDA |
| 10:35 - 11:00 |
Break |
|
| |
Session V: From
Single Genes to Transcriptional Profiling |
Chairs: Kevin Tracey/Jean-Paul Mira |
| 11:00 - 11:25 |
Can the Host Response be Used to Identify the
Pathogen? |
Lyle Moldawer, USA |
| 11:25 - 11:50 |
Lessons Learnt from well Defined PAMP's |
S E Calvano, USA |
| 11:50 - 12:15 |
Lessons Learnt from Controlled Experimental Settings |
Tom van der Poll, The Netherlands |
| 12:15 - 13:15 |
Lunch |
|
| 13:15 - 13:40 |
Potential and Limitations of Transcriptional
Profiling to Better Understand the Pathophysiology of Trauma and
Systemic Inflammation |
Lyle Moldawer, USA |
| 13:40 - 14:05 |
Clinical Utility of Transcriptional Profiling in
Human Sepsis |
Michael Bauer, GE |
| 14:05 - 14:30 |
Diagnostic Implications of Physiologic Diagnosis |
Andrew Seely, Canada |
| 14:30 - 15:00 |
BREAK |
|
| |
Session VI: Proteomics |
Chairs: Konrad Reinhart/Tom Van
der Poll |
| 15:00 - 15:25 |
Potential of Proteomics for Oncological Diagnosis |
Emmanuel Petricoin, USA |
| 15:25 - 16:00 |
Panel Discussion |
|
| 16:00 |
Closing Remarks |
Konrad Reinhart/John Marshall |
